Antibiofilm activity of Verbascum pinnatifidum Vahl. ethanolic extracts

Mehmet Göse, Nurcihan Hacıoğlu Doğru


Microbial biofilms pose health risks in clinical environments, food industry and drinking water systems. Microorganisms within biofilms more resistant to antibiotics and chemical agents than planktonic cells in suspension. New alternatives for controlling infections have been proposed focusing on the therapeutic properties of medicinal plants and their antibiofilm activities. Here, we investigated in vitro antibiofilm activities of ethanol extract of Verbascum pinnatifidum Vahl. for Escherichia coli NRRL B-3704, Pseudomonas aeruginosa ATCC 27853, Proteus vulgaris ATCC 13315, Acinetobacter baumanii ATCC 19606, Bacillus subtilis ATCC 6633, Staphylococcus aureus ATCC 25923, S. haemolyticus ATCC 43252 and Candida albicans ATCC 10231 test microorganisms based on crystal violet binding assay. The highest antibiofilm activity against biofilm formed by B. subtilis ATCC 6633 and S. haemolyticus ATCC 43252 at lowest MIC value 2.5 and 10 µg/mL, respectively. The current findings indicated that biofilm forming of bacteria could be potentially being managed using V. pinnatifidum plant extracts.


antibiofilm activity, Verbascum pinnatifidum Vahl.

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