Antioxidant potential of commercial hemp seed oils and CBD oil

Abstract

The present study investigates the antioxidant capacity of commercial hemp seed oils, 10% CBD enriched hemp seed oil and extra virgin olive oil used for comparison. Results indicate a difference in antioxidant activities among tested oils. CBD oil with IC₅₀ of 0.86 ± 0.06mg/ml was shown to be a better scavenger of hydroxyl radical and DPPH radical (IC₅₀ value of 5.99 ± 0.34 mg/ml) in comparison with other oils. CBD oil also had the best ability to reduce Fe³⁺ from ferricyanide at a concentration of 20 mg/ml (0.73) and the highest total antioxidant capacity (245 ± 35.16 GAE). Two commercial fresh hemp seed oils that showed small differences in antioxidant activity had better antioxidant properties than olive oil in three performed assays, while olive oil had the highest total antioxidant capacity. Hemp seed oil showed a lower antioxidant potential after a year of storage.