Frequency of isolation and antibiotic resistance patterns of bacterial isolates from wound infections

Zorica Stojanović-Radić, Marina Dimitrijević, Nikola Stanković, Ana Aleksić, Milica Pejčić


Six hundred and thirteen bacterial strains were isolated from wound swabs and the isolates were identified on the basis of growth on differential and selective media. In order to test the sensitivity of isolated strains to different antibiotics, the disc diffusion method, according to EUCAST protocol v 5.0 was used. The most common species isolated from wound swabs was Staphylococcus epidermidis (18.4%), followed by Staphylococcus aureus, Pseudomonas aeruginosa and Enterococcus faecalis (16.8%, 12.7% and 10.4%, respectively). The maximum resistance of Gram-positive cocci was observed to penicillin and the lowest to linezolid. Gram-negative bacteria showed the highest resistance to tetracyclines, while the same strains demonstrated the highest sensitivity to polypeptide antibiotics. Comparison of the resistance patterns of Gram-negative and Gram-positive bacterial strains showed significant difference in the tetracycline efficiency.


skin infections, wound swab, antibiotic resistance, S. epidermidis, S. aureus, P. aeruginosa

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