GC-MS metabolic profiling and free radical scavenging activity of Micromeria dalmatica

Milena Tihomirova Nikolova, Ina Yosifova Aneva, Strahil Berkov


Metabolite profile of acetone exudate and methanolic extract from aerial parts of Micromeria dalmatica Benth were analyzed by GC/MS. Palmitic and linolenic acids, hentriacontane,amyrin, quercetagetin 3,6,7-trimethyl ether, sucrose were identified among the main components in the acetone exudate. In the methanolic extract more than 100 chromatographic peaks were detected including alkanes, fatty alcohols, fatty acids, organic acids, phenolic acids, saccharides, polyoles, phytosterols and other. Most of the compounds were reported for the first time for the species. Hydromethanolic extract of M. dalmatica was studied for in vitro antioxidant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical-scavenging activity. The inhibitory concentration (IC50) of extract was calculated to be 21.36 µg/mL. The received result shows high antioxidant potential of Micromeria dalmatica extract which provide scientific support for the use of the plant as herbs and spices.


alkanes, DPPH, fatty acid, carbohydrate, flavonoid, lipid, phenolic

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