Cell deaths and their associated mechanisms

Phey Liana, Masagus Irsan Saleh, Desi Oktariana, Tungki Pratama Umar, DOI: 10.46793/BiolNyss.16.2.8L

Abstract


Cell death is a crucial process in every organism, maintaining a balance between the number of new cells generated through mitosis and the number of damaged or unnecessary cells removed from the body. It happens from the embryonic process throughout every life stage of a human being. Regulated cell death, known as apoptosis, is the most common form, while accidental or uncontrolled cell death, known as necrosis, is associated with pathological processes. In addition to these types of cell death, there are numerous other types, including necroptosis (a controlled cell death with an inflammatory process) and autophagy (mainly a part of the immune process). It is important to note that inhibition of regulated cell death can impact the normal cell cycle and can lead to drug resistance. A classic example of dysfunctional cell death regulation is cancer development. This review summarizes cell death types and their associated mechanisms.

Keywords


accidental cell death, apoptosis, necrosis, regulated cell death

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References


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